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A metabolic atlas of blood cells in young and aged mice identifies uridine as a metabolite to rejuvenate aged hematopoietic stem cells - Nature Aging

https://www.nature.com/articles/s43587-024-00669-1

Zeng, Shi, Han, Hu, Li, Wei et al. present a metabolic atlas covering 15 hematopoietic cell types from young and aged mice. By screening metabolites that are depleted with age, they identify that uridine treatment can restore function in aged hematopoietic stem cells.

A metabolic atlas of blood cells in young and aged mice identifies uridine as a metabolite to rejuvenate aged hematopoietic stem cells - Nature Aging

Through metabolic screening, we identified uridine as a potential regulator to rejuvenate aged HSPCs.

2 comments

toast

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Interestingly (from Wikipedia):

...plasma uridine levels rose 1.8-fold 30 minutes after beer ingestion, suggesting, at the very least, conflicting data. On the other hand, ethanol on its own (which is present in beer) increases uridine levels, which may explain the raise of uridine levels in the study by Yamamoto et al.

beer good?

Timoth

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As someone with no scientific training or expertise, I can confirm, beer good.