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Zeng, Shi, Han, Hu, Li, Wei et al. present a metabolic atlas covering 15 hematopoietic cell types from young and aged mice. By screening metabolites that are depleted with age, they identify that uridine treatment can restore function in aged hematopoietic stem cells.

IL-11 is identified as a key regulator of ERK–AMPK–mTORC1 signalling, metabolism, inflammation and age-related disease and lifespan in mouse and human.

Researchers publishing in Aging have found a molecule linking exercise to the inhibition of cellular senescence, one of the hallmarks of aging. Exercise against senescence We recently […]

Researchers have published a method of rescuing cells from damaged mitochondria and cellular senescence, potentially alleviating major aspects of aging. Bad mitochondria must be […]

An analysis of oral microbes in older adults has indicated an association between microbial diversity and executive function performance [1]. […]

In the newest study by the Interventions Testing Program, 16α-hydroxyestriol and canagliflozin significantly increased lifespan in male mice but were deleterious for females [1]. The golden standard The Interventions Testing Program, […]