Top left is Imoen, from the Baldur's Gate games. This image is from the first game.
Notice: I have not played BG3, so I do not know if the spawn of the Lord of Murder is still the main character of the story, or if his "sister" Imoen is involved.
Oof. Here goes (left to right. Starting top row.
Aes Sedai (wot), bam bam, the cow from rokos modern life, Spyro, the weird sister from arrested development, Geralt's ginger cousin who always comes to the cookout even though he doesn't have an invite.
It's not Aes Sedai, and John Galt was right that the last one is Alistair, but otherwise those are the correct characters!
They are all characters in mixed media.
...technically correct.
I think it's something along the lines of the all have siblings.
Edit:typo
lol as Trapp would say: "that's not what we're going for" but assuming you meant 'siblings', you're getting warmer