I did the ascent with a +23 cursed staff with Wondrous Resin

After beating Yog, I curse infused my staff for the ascent. With Wonderous Resin, it was kind of fun. It would only zap random things. Kinda hard to do damage, but once in a while it would smack someone for 95 damage, or ooze everyone. Mostly, I used melee. I got lots and lots of challenge arenas.

One time it zapped corrosion, toxic gas, and corrosion all in a row in the same room versus 6 ghouls. Super effective!

Later on, I planted a sunseed to heal as soon as I ascended some stairs. It didn't take long for an enemy to poke their head into the room, so I zapped him. Randomly got the stasis effect! When it ended, I was fully healed and there were 4 enemies in the room with 3 more just outside. That was a fight for my life! Especially since enemy evasion is so damned high on the ascent.

Oh, and I also got the stasis effect during the final phase of Dwarf King... ☹️

Thankfully, I was using Disintegration on my staff at the time and could hit the King from across the room.